PMDD much more severe form of premenstrual syndrome (PMS)

exact cause is not known. It may be an abnormal reaction to normal hormone changes that happen with each menstrual cycle. The hormone changes can cause a serotonin deficiency.

Risk Factors

  • Women with a family history of PMS or PMDD  
  • Women with a personal or family history of depression, postpartum depression, or other mood disorders